Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

Research in Cell Stem Cell describes a 3D pluripotent stem cell culture technique for generating human brain organoids resembling the MGE and cortical domains. Movie of neuron migration below. Calcium imaging was performed using a Nikon TS-100, electrophysiology in conjunction with a Nikon FN-1, and imaging of fixed brain slices using a Nikon C1 confocal microscope.

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