Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration
August 04, 2017, via Cell Stem Cell
Research in Cell Stem Cell describes a 3D pluripotent stem cell culture technique for generating human brain organoids resembling the MGE and cortical domains. Movie of neuron migration below. Calcium imaging was performed using a Nikon TS-100, electrophysiology in conjunction with a Nikon FN-1, and imaging of fixed brain slices using a Nikon C1 confocal microscope.