Gephyrin-binding Peptides Visualize Postsynaptic Sites and Modulate Neurotransmission

Researchers have developed fluorescent cell-permeable “super-binding” peptides for specific labeling of gephyrin - a marker of the inhibitory postsynaptic density - demonstrating conventional and super-resolution imaging of inhibitory postsynaptic sites for the first time. These peptides also act as modulators of inhibitory neurotransmission. The authors hope to expand the desigin and use of fluorescent “super-binding” peptides to other cellular targets.

Learn More @ Nature Chemical Biology

Recent News and Updates

See all News

Share this article: