Opiates Increase the Number of Hypocretin-Producing Cells in Human and Mouse Brain and Reverse Cataplexy in a Mouse Model of Narcolepsy

New research in Science Translational Medicine finds that heroin addicts have much higher levels of hypocretin-producing neurons. Conversely, narcolepsy is caused by loss of hypocretin neurons, and can be restored via administration of morphine. Imaging was performed with a Nikon upright microscope.

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