Embryonic Rat Thoracic Aorta Medial Layer Myoblasts (A-10 Line)
The clonal cell line A-10 was derived from the excised thoracic aorta of an embryonic rat (Rattus norvegicus) from the strain DB1X. The thoracic aorta is a branch of the descending aorta, which transports blood from the heart to the other organs and parts of the body. This arbitrary anatomic entity is generally considered to extend from the arch of the aorta to the diaphragm. The cells grow adherently and exhibit myoblast morphology, possessing many of the properties characteristic of smooth muscle cells. Cellular products include myokinase, creatine phosphokinase, and myosin. A-10 cells produce spontaneous action potentials at the stationary phase of the growth cycle and exhibit an increase in activity of the enzymes myokinase and creatine phosphokinase.