Live-Cell Imaging

An increasing number of investigations are using live-cell imaging techniques to provide critical insight into the fundamental nature of cellular and tissue function, especially due to the rapid advances that are currently being witnessed in fluorescent protein and synthetic fluorophore technology.

Review Articles

Interactive Tutorials


Cell Motility

Explore cell motility in differential interference contrast (DIC) microscopy.


Confocal Microscopy

Enjoy the beauty of autofluorescence in thick sections of animal and plant tissues.


Differential Interference Contrast (DIC)

Compare specimen contrast using these complementary imaging techniques.

Image Comparisons • Movies

Fluorescence Microscopy

Cells and tissues examined with synthetic fluorophores in fluorescence microscopy.


Phase Contrast

Specimen viewfields examined using positive and negative phase contrast.

Image Comparisons

Selected Literature References

Contributing Authors

Michael E. Dailey - Department of Biological Sciences and Neuroscience Program, 369 Biology Building, University of Iowa, Iowa City, Iowa, 52242.

Daniel C. Focht - Bioptechs Inc., 3560 Beck Road, Butler, Pennsylvania, 16002.

Alexey Khodjakov and Conly L. Rieder - Wadsworth Center, New York State Department of Health, Albany, New York, 12201, and Marine Biological Laboratory, Woods Hole, Massachusetts, 02543.

George H. Patterson and Jennifer Lippincott-Schwartz - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20892.

David W. Piston - Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, 37232.

Melpomeni Platani - Gene Expression Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117, Heidelberg, Germany.

Kenneth R. Spring - Scientific Consultant, Lusby, Maryland, 20657.

Jason R. Swedlow and Paul D. Andrews - Division of Gene Regulation and Expression, MSI/WTB Complex, University of Dundee, Dundee DD1 5EH, Scotland.

Yu-li Wang - University of Massachusetts Medical School, 377 Plantation Street, Suite 327, Worcester, Massachusetts, 01605.

Jennifer C. Waters - Nikon Imaging Center, LHRRB Room 113C, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts, 02115.

Joel S. Silfies and Edward G. Lieser - Nikon Instruments, Inc., 1300 Walt Whitman Road, Melville, New York, 11747.

Tony B. GinesAlex B. CokerNathan S. ClaxtonScott G. OlenychJohn D. Griffin, and Michael W. Davidson - National High Magnetic Field Laboratory, 1800 East Paul Dirac Dr., The Florida State University, Tallahassee, Florida, 32310.

Share this page:

Live-Cell Imaging


Review Articles

Interactive Tutorials


Literature References

Contributing Authors