Raccoon Uterus Fibroblast Cells (PL 1 Ut Line)
The PL 1 Ut cell line was derived from the uterine tissue of an adult female North American raccoon (Procyon lotor). The cells exhibit fibroblast-like morphological characteristics and grow adherently to glass and polymer surfaces in culture. Studies have shown that PL 1 Ut cells are susceptible to an array of viruses, including herpes simplex virus, reovirus 3, and vesicular stomatitis (Ogden strain). The line is commonly utilized in the propagation of such viruses for research purposes, and has been particularly useful in investigations of feline and canine viral diseases. PL 1 Ut cells are resistant to infection with poliovirus 2, coxsackieviruses A9 and B5, vaccinia, and adenoviruses 2 and 5.