Single Molecule Blinking Microscopy Literature References
The term Blink microscopy refers to the use of single-molecule imaging to exploit the fluctuating emission of fluorophores that are capable of photoswitching from a bright to a dark state (or from one emission wavelength to another) to construct superresolution images. Among the common blink techniques are ground state depletion with individual molecule return (GSDIM), reversible photobleaching microscopy (RPM), and dSTORM (direct STORM).
Recommended Literature
- Cordes, T., Strackharn, M., Stahl, S. W., Summerer, W., Steinhauer, C., Forthmann, C., Puchner, E. M., Vogelsang, J., Gaub, H. E. and Tinnefeld, P. Resolving single-molecule assembled patterns with super-resolution blink-microscopy. Nano Letters 10: 645-651 (2010).
- Heilemann, M., van de Linde, S., Mukherjee, A. and Sauer, M. Super-resolution imaging with small organic fluorophores. Angewandte Chemie International Edition 48: 6903-6908 (2009).
- Heilemann, M., van de Linde, S., Schuttpelz, M., Kasper, R., Seefeldt, B., Mukherjee, A., Tinnefeld, P. and Sauer, M. Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes. Angewandte Chemie International Edition 47: 6172-6176 (2008).
- Lemmer, P., Gunkel, M., Baddeley, D., Kaufmann, R., Urich, A., Weiland, Y., Reymann, J., Muller, P., Hausmann, M. and Cremer, C. SPDM: Light microscopy with single-molecule resolution at the nanoscale. Applied Physics B: Lasers and Optics 93: 1-12 (2008).
- Schuster, J., Brabandt, J. and von Borczyskowski, C. Discrimination of photoblinking and photobleaching on the single molecule level. Journal of Luminescence 127: 224-229 (2007).
- Steinhauer, C., Forthmann, C., Vogelsang, J. and Tinnefeld, P. Superresolution microscopy on the basis of engineered dark states. Journal of the American Chemical Society 130: 16840-16841 (2008).
- Steinhauer, C., Jungmann, R., Sobey, T. L., Simmel, F. C. and Tinnefeld, P. DNA origami as a nanoscopic ruler for super-resolution microscopy. Angewandte Chemie International Edition 48: 8870-8873 (2009).
- van de Linde, S., Endesfelder, U., Mukherjee, A., Schuttpelz, M., Wiebusch, G., Wolter, S., Heilemann, M. and Sauer, M. Multicolor photoswitching microscopy for subdiffraction-resolution fluorescence imaging. Photochemical & Photobiological Sciences 8: 465-469 (2009).
- van de Linde, S., Kasper, R., Heilemann, M. and Sauer, M. Photoswitching microscopy with standard fluorophores. Applied Physics B: Lasers and Optics 93: 725-731 (2008).
- van de Linde, S., Wolter, S., Heilemann, M. and Sauer, M. The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging. Journal of Biotechnology 149: 260-266 (2010).
- Vogelsang, J., Cordes, T., Forthmann, C., Steinhauer, C. and Tinnefeld, P. Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy. Proceedings of the National Academy of Sciences (USA) 106: 8107-8112 (2009).
- Vogelsang, J., Kasper, R., Steinhauer, C., Person, B., Heilemann, M., Sauer, M. and Tinnefeld, P.A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes. Angewandte Chemie International Edition 47: 5465-5469 (2008).
Additional Literature Sources
- Aitken, C. E., Marshall, R. A. and Puglisi, J. D. An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments. Biophysical Journal 94: 1826-1835 (2008).
- Cordes, T., Vogelsang, J., Anaya, M., Spagnuolo, C., Gietl, A., Summerer, W., Herrmann, A., Mullen, K. and Tinnefeld, P. Single-molecule redox blinking of perylene dimide derivatives in water. Journal of the American Chemical Society 132: 2404-2409 (2010).
- Cordes, T., Vogelsang, J. and Tinnefeld, P. On the mechanism of Trolox as antiblinking and antibleaching reagent. Journal of the American Chemical Society 131: 5018-5019 (2009).
- Gensch, T., Bohmer, M. and Aramendia, P. F. Single molecule blinking and photobleaching separated by wide-field fluorescence microscopy. Journal of Physical Chemistry 109:6652-6658 (2005).
- Hu, D. and Orr, G. Nanometer resolution imaging by single molecule switching. Nano Reviews 1: 5122-5123 (2010).
- Lidke, K., Rieger, B., Jovin, T. and Heintzmann, R. Superresolution by localization of quantum dots using blinking statistics. Optics Express 13: 7052-7062 (2005).
- Rasnik, I., McKinney, S. A. and Ha T. Nonblinking and long-lasting single-molecule fluorescence imaging. Nature Methods 3: 891-893 (2006).
- Rundquist, I. and Enerback, L. Millisecond Fading and Recovery Phenomena in Fluorescent Biological Objects. Histochemistry and Cell Biology 47: 79-87 (1975).
- Tang, J. Random on-off telegraphic signaling in single nanoparticles and molecules. Nano Reviews 1: 5031-2 (2010).
- van de Linde, S., Sauer, M. and Heilemann, M. Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores. Journal of Structural Biology 164: 250-254 (2008).
- Vogelsang, J., Cordes, T., Forthmann, C., Steinhauer, C. and Tinnefeld, P. Intrinsically resolution enhancing probes for confocal microscopy. Nano Letters 10: 672-679 (2010).
- Westphal, V. and Hell, S. W. Nanoscale resolution in the focal plane of an optical microscope. Physical Review Letters 94: 143903-4 (2005).
- Widengren, J. Fluorescence-based transient state monitoring for biomolecular spectroscopy and imaging. Journal of the Royal Society Interface 7: 1135-1144 (2010).
- Zondervan, R., Kulzer, F., Orlinskii, S. B. and Orrit, M. Photoblinking of rhodamine 6G in poly(vinyl alcohol): Radical dark state formed through the triplet. Journal of Physical Chemistry A 107: 6770-6776 (2003).
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