Quantum Dot Literature References

Quantum dots are inorganic semiconductor nanocrystals composed of a cadmium selenide (CdSe) core surrounded by a zinc sulphide (ZnS) shell that exhibit fluorescent properties due to confined excition emission. A passivation layer and hydrophilic coating must be applied to quantum dots for biological applications and they must also be conjugated to streptavidin or antibodies for targeting. The fluorescence emission profile of quantum dots is remarkably symmetrical and generally exhibits a large quantum yield, while their broad absorption profile enables them to be excited over a large wavelength range.

Recommended Literature

Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan, G., Wu, A. M., Gambhir, S. S. and Weiss, S. Quantum dot for live cells, in vivo imaging, and diagnostics. Science 307: 538-544 (2005).
Jaiswal, J. K. and Simon, S. M. Potentials and pitfalls of fluorescent quantum dots for biological imaging. Trends in Cell Biology 14: 497-504 (2004).
Alivisatos, A. P., Gu, W. and Larabell, C. Quantum dots as cellular probes. Annual Review of Biomedical Engineering 7: 55-76 (2005).
Deerinck, T. J. The application of fluorescent quantum dots to confocal, multiphoton, and electron microscopic imaging. Toxicologic Pathology 36: 112-116 (2008).
Resch-Genger, U., Grabolle, M., Cavaliere-Jaricot, S., Nitschke, R. and Nann, T. Quantum dots versus organic dyes as fluorescent labels. Nature Methods 5: 763-775 (2008).
Alivisatos, A. P. The use of nanocrystals in biological detection. Nature Biotechnology 22:47-52 (2004).
Gao, X., Yang, L., Petros, J. A., Marshall, F. F., Simons, J. W. and Nie, S. In vivo molecular and cellular imaging with quantum dots. Current Opinion in Biotechnology 16: 63-72 (2005).
Bruchez, M. P. Turning all the lights on: Quantum dots in cellular assays. Current Opinion in Chemical Biology 9: 533-537 (2005).
Li, Z. B., Cai, W. and Chen, X. Semiconductor quantum dots for in vivo imaging. Journal of Nanoscience and Nanotechnology 7: 2567-2581 (2007).
Chang, Y., Pinaud, F., Antelman, J. and Weiss, S. Tracking bio-molecules in live cells using quantum dots. Journal of Biophotonics 1: 287-298 (2008).
Jaiswal, J. K., Goldman, E. R., Mattoussi, H. and Simon, S. M. Use of quantum dots for live cell imaging. Nature Methods 1: 73-78 (2004).
Bentolila, L. A., Ebenstein, Y. and Weiss, S. Quantum dots for in vivo small-animal imaging.Journal of Nuclear Medicine 50: 493-496 (2009).
Pathak, S., Cao, E., Davidson, M. C., Jin, S. and Silva, G. A. Quantum dot applications to neuroscience: New tools for probing neurons and glia. The Journal of Neuroscience 26:1893-1895 (2006).
Medintz, I. L. and Mattoussi, H. Quantum dot-based resonance energy transfer and its growing application in biology. Physical Chemistry Chemical Physics 11: 17-45 (2009).
Zhang, Y., Kaji, N., Tokeshi, M. and Baba, Y. Nanobiotechnology: Quantum dots in bioimaging. Expert Review of Proteomics 4: 565-572 (2007).

Additional Literature Sources

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Algar, W. R. and Krull, U. J. Quantum dots as donors in fluorescence resonance energy transfer for the bioanalysis of nucleic acids, proteins, and other biological molecules.Analytical and Bioanalytical Chemistry 391: 1609-1618 (2008).
Arya, H., Kaul, Z., Wadhwa, R., Taira, K., Hirano, T. and Kaul, S. C. Quantum dots in bio-imaging: Revolution by the small. Biochemical and Biophysical Research Communications 329: 1173-1177 (2005).
Azzazy, H. M. E. and Mansour, M. M. H. In vitro diagnostic prospects of nanoparticles.Clinica Chimica Acta 403: 1-8 (2009).
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Bruchez, M. P., Moronne, M., Gin, P., Weiss, S. and Alivisatos, A. P. Semiconductor nanocrystals as fluorescent biological labels. Science 281: 2013-2016 (1998).
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Clapp, A. R., Medintz, I. L., Fisher, B. R., Anderson, G. P. and Mattoussi, H. Can luminescent quantum dots be efficient energy acceptors with organic dye donors? Journal of the American Chemical Society 127: 1242-1250 (2005).
Dahan, M. From analog to digital: Exploring cell dynamics with single quantum dots.Histochemistry and Cell Biology 125: 451-456 (2006).
Dahan, M., Levi, S., Luccardini, C., Rostaing, P., Riveau, B. and Triller, A. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science 302: 442-445 (2003).
Debbage, P. and Jaschke, W. Molecular imaging with nanoparticles: Giant roles for dwarf actors. Histochemistry and Cell Biology 130: 845-875 (2008).
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Delehanty, J. B., Boeneman, K., Bradburne, C. E., Robertson, K. and Medintz, I. L. Quantum dots: A powerful tool for understanding the intricacies of nanoparticle-mediated drug delivery. Expert Opinion on Drug Delivery 6: 1091-1112 (2009).
Derfus, A. M., Chan, W. C. W. and Bhatia, S. N. Intracellular delivery of quantum dots for live cell labeling of organelle tracking. Advanced Materials 16: 961-966 (2004).
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Doose, S. Optical amplification from single excitons in colloidal quantum dots. Small 3:1856-1858 (2007).
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