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Fluorescent Turtle Embryo Wins Forty-Fifth Annual Nikon Small World Competition

Nikon Instruments Inc. today announced the winners of the forty-fifth annual Nikon Small World Photomicrography Competition. First place was awarded to microscopy technician Teresa Zgoda and recent university graduate Teresa Kugler for their visually stunning and painstakingly prepared photo of a turtle embryo. Captured using fluorescence and stereo microscopy, the colorful final image is a masterful example of image-stitching. 

Learn More @ Nikon Small World

How ‘magic angle’ graphene is stirring up physics

Have you heard about the newly discovered graphene ‘magic angle’? Overlaying a pair of graphene sheets with their relative rotation set to the ‘magic angle’ results in unexpected superconductivity. There is also the possibility that this mechanism may be similar to those governing high-temperature superconductors.

Learn More @ Nature

Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells

Researchers have succeeded in the direct reprogramming of human somatic cells into induced neural plate border stem cells (iNPBSCs) via ectopic expression of 4 factors. The iNPBSCs are self-renewing, multipotent, and easily modified with CRISPR/Cas9, with potential for applications in regenerative medicine.

Learn More @ Cell Stem Cell

3D nanofabrication by volumetric deposition and controlled shrinkage of patterned scaffolds

The Boyden lab at MIT does it again with new Implosion Fabrication (ImpFab). Like Expansion Microscopy, ImpFab also exploits the shrinking/swelling properties of hydrogels to manipulate object size. ImpFab uses a hydrogel scaffold for arranging structures while at an easily workable size, followed by dehydration of the gel to shrink the entire assembly to a nano size. Importantly, this allows for new geometries that can’t be made through the typical process of assembly by stacking layers.

Learn More @ Science

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Alpha-catenin is a key protein linking the actin cytoskeleton with intercellular adhesions. Researchers at the University of Toronto shine new light on the mechanisms of tension-dependent F-actin binding by alpha-catenin.

Scratch wound assays for this study were performed using a Nikon IM-Q incubated microscope, and confocal imaging in part with a Nikon A1R resonant scanning system.

Learn More @ Nature Communications

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