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Researchers Turn Light Upside Down

New metasurface design based on boron nitride allows for generation of hyperbolic surface polaritons from infrared light.  Imaging performed using near-field scanning microscopy. Potential applications include miniaturization of optical devices. 

Learn More @ PHYS.ORG

High-Throughput, Image-Based Screening of Pooled Genetic-Variant Libraries

New high-throughput screening method utilizes FISH-based fluorescent barcoding to allow determination of genotype from phenotype of individuals in a pooled library of genetic variants.

This method is used to identify an improved version of the fluorescent protein YFAST from over 60,000 variants. Custom high-throughput system configured on a Nikon Ti-U inverted microscope.

Learn More @ Nature Methods

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Dentate Granule Cell Recruitment of Feedforward Inhibition Governs Engram Maintenance and Remote Memory Generalization

'Remember to Look up at the Stars': The Best Stephen Hawking Quotes

Rotation of Endosomes Demonstrates Coordination of Molecular Motors During Axonal Transport

Autism's Social Deficits Are Reversed by an Anti-Cancer Drug

Heterogeneous Localization of Membrane Proteins in Staphylococcus Aureus

The Ancestral Retinoic Acid Receptor Was a Low-Affinity Sensor Triggering Neuronal Differentiation

Imaging the Imperceptible

Researchers Turn Light Upside Down

A Robotic Multidimensional Directed Evolution Approach Applied to Fluorescent Voltage Reporters

Researchers Have Finally Created a Tool to Spot Duplicated Images Across Thousands of Papers

High-Throughput, Image-Based Screening of Pooled Genetic-Variant Libraries

SCIENCE with/in/sight: 2018 Koch Institute Image Awards

Alteration of Rocks by Endolithic Organisms Is One of the Pathways for the Beginning of Soils on Earth

Under Victorian Microscopes, An Enchanted World

Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues

Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues

Polymer Coating Glass to Improve the Protein Antifouling Effect

Human Brain Organoids on a Chip Reveal the Physics of Folding

Remote Refocus Enables Class-Leading Spatiotemporal Resolution in 4D Optical Microscopy

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability