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Mutating DNA Caught on Film

New microfluidic platform allows researchers to watch DNA mutate! To see the mutations, the team built 1000 microscopic channels into a computerlike chip and placed a single bacterial cell at the closed end of each the channel.

Learn More @ Science

Researchers Turn Light Upside Down

New metasurface design based on boron nitride allows for generation of hyperbolic surface polaritons from infrared light.  Imaging performed using near-field scanning microscopy. Potential applications include miniaturization of optical devices. 

Learn More @ PHYS.ORG

High-Throughput, Image-Based Screening of Pooled Genetic-Variant Libraries

New high-throughput screening method utilizes FISH-based fluorescent barcoding to allow determination of genotype from phenotype of individuals in a pooled library of genetic variants.

This method is used to identify an improved version of the fluorescent protein YFAST from over 60,000 variants. Custom high-throughput system configured on a Nikon Ti-U inverted microscope.

Learn More @ Nature Methods

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