The Ever-Tightening Job Market for Ph.D.s
August 02, 2017, via The Atlantic
Thought-provoking article on tight job market for PhD. Don't despair though, there are plenty of great career opportunities for Ph.D.s at Nikon Instruments!
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Mitotic Progression Following DNA Damage Enables Pattern Recognition Within Micronuclei
August 01, 2017, via Nature
Fighting cancer with radiotherapy and chemotherapy relies on DNA double-strand breaks (DSBs) to kill tumour cells. New research in Nature now shows that tumour cell division following DSBs results in the formation of micronuclei, which has a number of important implications for treatment. Imaging was performed in part using a Nikon 80i upright microscope with NIS-Elements software.
Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State
July 28, 2017, via Biophysical Journal
Penn State researchers have published a new model of kinesin processivity in Biophysical Journal. Kinesin is a motor protein powered by ATP that moves cargo along microtubule filaments in eukaryotic cells. Single molecule TIRF imaging was performed using a Nikon TE2000 inverted microscope.
Mechanical Strain Sensing Implicated in Cell Shape Recovery in Escherichia coli
July 27, 2017, via Nature Microbiology
New research on bacterial cell shape suggests mechanical sensing by the elongasome is important for shape regulation. Imaging was performed using a Nikon A1R resonant-scanning confocal microscope.
Four Scientific Journals Accept Fake Study About "Midi-Chlorians" From Star Wars
July 26, 2017, via IFLScience!
To think, we were this close to having a “scientific study” about #midichlorians published. Beware predatory journals!
Nikon Turns 100!
July 25, 2017, via Nikon
On this day in 1917 two of Japan’s leading optical manufacturers merged to form Nippon Kogaku K. K., known today as Nikon. We look forward to serving the imaging community for the next 100 years!
Nikon Small World Exhibition at the Bruce Museum
July 25, 2017, via Greenwich Sentinel
Catch the next stop of our Nikon Small World gallery at the Bruce Museum in Greenwich, CT from July 29 - October 29!
Actomyosin Drives Cancer Cell Nuclear Dysmorphia and Threatens Genome Stability
July 24, 2017, via Nature Communications
Research in Nature Communications identifies two subunits of the myosin phosphatase complex that antagonize actomyosin contractility, which is shown to be a major determinant of nuclear shape. Live-cell imaging was performed using a Nikon TE2000 inverted microscope with spinning disk
Purified and Fluorescent-Labeled MinD and MinE
July 20, 2017, via YouTube
Check out these beautiful patterns made by purified MinD and MinE on artificial membrane, as visualized on a Nikon Ti-E with TIRF! Images acquired by Dr. Anthony Vecchiarelli while at the National Institutes of Health (NIH).
Celebrating Nikon's 100th Anniversary
July 18, 2017, via Nikon
Check out Nikon’s special 100th anniversary site! Learn more about our history, enjoy commemorative videos, and take a look at some special merchandise.
Biophysical and Biomolecular Determination of Cellular Age in Humans
July 14, 2017, via Nature Biomedical Engineering
Ever wonder what your cellular age is? New research in Nature Biomedical Engineering shows that biophysical features such as morphology and migratory potential are better predictors of cellular age than previous metrics. Imaging was performed using a Nikon TE2000 inverted microscope.
Versatile Synthetic Alternatives to Matrigel for Vascular Toxicity Screening and Stem Cell Expansion
July 11, 2017, via Nature Biomedical Engineering
Researchers from University of Wisconsin-Madison have published a new method in Nature Biomedical Engineering for optimizing synthetic cell culture substrates for use in both vascular network growth and stem cell expansion in vitro. Imaging was performed using a Nikon A1R resonant-scanning confocal microscope.
Nikon Imaging Center at UC San Diego
July 10, 2017, via Nikon Instruments
We are very happy to announce the development of the latest Nikon Imaging Center at UC San Diego!
Acclimatization of Symbiotic Corals to Mesophotic Light Environments Through Wavelength Transformation by Fluorescent Protein Pigments
July 07, 2017, via Proceedings of the Royal Society B
The symbiotic algae of reef #coral perform photosynthesis, providing nutrients for both organisms. However, new research in Proceedings of the Royal Society B shows that in deeper water corals produce more red fluorescent proteins. The red fluorescent light better penetrates algae-containing tissues than the blue light typically found in deep water.
Imaging of Jurassic Fossils from the Talbragar Fish Bed Using Fluorescence, Photoluminescence, and Elemental and Mineralogical Mapping
July 07, 2017, via PLoS ONE
Open-access research in PLoS ONE establishes fluorescence microscopy as a useful tool for studying otherwise unseen anatomical details in fossils. Imaging of Jurassic era specimens was performed using a Nikon Ti-U microscope.
Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips
July 05, 2017, via Cell Press
A new platform for assessing off-target CRISPR-Cas protein binding and nuclease activation is introduced in new research published in Cell. Fluorescence imaging was performed using a Nikon Ti-E inverted microscope with TIRF illumination.
3D Virus Cam Catches Germs Red-Handed
July 03, 2017, via Duke University
Researchers at Duke University have demonstrated a microscope technique using active feedback to keep a fluorescent protein-labeled lentivirus in focus as it moves in 3D.
Microscience Microscopy Congress 2017
July 02, 2017, via Nikon Instruments
Come find us at Microscience Microscopy Congress 2017, Booth #723 in Manchester, UK from July 3-6! We'll be showcasing the new Ti2 and holding several workshops.
Altering the Threshold of an Excitable Signal Transduction Network Changes Cell Migratory Modes
July 02, 2017, via Nature Cell Biology
Research appearing in Nature Cell Biology shows that different cell migratory modes arise from varying threshold levels for the excitation of related signal transduction pathways. Change in cell migratory mode is an important aspect of metastasis.
TIRF imaging of signal transduction and the cytoskeleton was performed using a Nikon Ti-E inverted microscope.
Optogenetic Protein Clustering Through Fluorescent Protein Tagging and Extension of CRY2
July 01, 2017, via Nature Communications
New tool for light-induced protein homo-oligomerization using the CRY2 protein introduced in research published in Nature Communications. Potential applications include investigation and control of rapid signaling dynamics in living systems.
Live-cell imaging was performed with a Nikon A1R resonant-scanning #confocal microscope and fixed-cell imaging with the Nikon N-SIM super-resolution structured illumination system.
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