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July 01, 2017, via Nature Biomedical Engineering
Is light-sheet microscopy the future of imaging for pathology? Researchers have now applied the technique towards quick evaluation of specimens in their native 3D context.
June 30, 2017, via MIT OPENCOURSEWARE
Want to learn more about imaging for science and engineering? Check out this free MIT OpenCourseWare online class by Felice Frankel!
June 30, 2017, via Nature Methods
New research published in Nature Methods details the use of DNA origami for quantifying protein copy number in immunofluorescence-based super-resolution microscopy.
June 20, 2017, via Cell
New research in Cell finds that the rate of synthesis for leading and lagging strand DNA polymerases are uncoordinated and can vary up to 10-fold. Furthermore, when DNA polymerase activity is paused, the rate of DNA unwinding by helicase drops by ~80% to allow for recoupling. Imaging was performed using a Nikon TE2000-U with 100x (NA 1.49) TIRF objective.
June 08, 2017, via Biophysical Journal
A new method published in Biophysical Journal tackles one of the most pervasive issues in super-resolution microscopy – 3D drift correction. The z-position of fiducial markers is jointly determined by spot width without the need for additional optics or imaging multiple planes.
June 07, 2017, via Nature Scientifc Reports
High content combined FRET, PLA, and Pearson’s correlation for high accuracy colocalization analyses? Learn how with the Nikon A1R confocal microscope.
June 06, 2017, via Nature
New research in Nature shows that nucleotide repeat expansion disorders, such as ALS, require a certain number of repeats before transcripts form foci in the nucleus, with in vitro experiments showing that multivalent base-paring can lead to gelation of RNA.
Imaging was performed using a Nikon Ti-E inverted research microscope with Yokogawa X1 spinning disk.
June 05, 2017, via Nikon Instruments
Nikon's recently introduced a new 100x silicone immersion objective (NA = 1.35) for super-resolution and multi-modal microscopy of thick specimens. The CFI SR HP Plan Apochromat Lambda S 100XC Sil objective and silicone immersion medium enable super-resolution imaging of thick specimens and offers correlative imaging capabilities.
May 25, 2017, via TEDx Talks
We're happy to support the efforts of our Nikon Small World alumni! Check out long time Nikon Small World supporter and Hall of Famer, Wim van Egmond’s latest TED talk, A Journey Inside the Mircro-world.
May 22, 2017, via Nikon Instruments
We would like to invite you to join us for a demo at the European Light Microscopy Initiative (ELMI) this week! We’ll be showcasing the new Ti2 as well as several confocal solutions.
May 18, 2017, via Nature Protocols
Learn how to do DNA-PAINT single molecule localization microscopy on your Nikon TIRF system with this new protocol!
May 16, 2017, via The Dr. Oz Show
Nikon's Eclipse Ti2 tissue culture microscope recently appeared on a Dr. Oz Show episode about HeLa cells, along with a couple special guests!
May 16, 2017, via Optical Society of America
Here’s a new open-access article in Biomedical Optics Express demonstrating superresolution Structured Illumination (SIM) fluorescence and quantitative phase microscopies on the same system.
May 15, 2017, via Cell Death & Disease
Research in Cell Death & Disease shows that autophagy is essential for hearing in mice. Atg5-deficient mice demonstrated auditory hair cell degeneration and congenital hearing loss. Imaging was performed using a Nikon A1R confocal microscope.
May 14, 2017, via Nature
Traditionally, access to scientific research has been regulated by paywalls. But with new methods for electronic sharing, how will the scientific publishing industry adapt? Check out this recent news article from Nature.
April 27, 2017, via Nature
Here’s a news article from Nature discussing investments by California in stem-cell research. With almost 3 billion dollars on the books, will treatments emerge before funding runs out?
April 26, 2017, via Biophysical Journal
Live-cell super-resolution imaging reveals the correlated retrograde flow of both the cortical actin cytoskeleton and the plasma membrane in T cell immunological synapses. TIRF-SIM imaging was performed in part using a Nikon N-SIM system.
April 25, 2017, via Nature Photonics
STORM on a chip? New research uses a slab waveguide to generate an evanescent wave over a wide field of view for flexible TIRF illumination unconstrained by the objective lens.
April 21, 2017, via Nature Communications
Open-access research in Scientific Reports details a new FRET-based sensor for detection of cAMP concentration in different intracellular compartments of cardiac myocytes. Imaging was performed in part using a Nikon TE-2000 inverted research microscope.
April 20, 2017, via Science
The EMBL has announced plans to build a new lab in Barcelona to focus on the study of tissues and organs!
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